It is almost impossible to completely protect your food from every single microbe. Food needs to initially be packed in a sterile enviroment. Cooking at sufficiently high temperatures kills most bacteria. Keeping food it in the fridge or freezer slows bacterial growth. So overall its all about temp control to minimize/ prevent contamination. But over time microbes will grow on the food and will become inedible.
Depends what kind of bugs…. bacterial ones of big creepy ones like ants!! for the big ones dont leave it out overnight, once i left a cake out and the next day it was black with ants…. ewwwww
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